Bioreactors
Design, Operation and Novel Applications
1. Auflage April 2016
XX, 494 Seiten, Hardcover
125 Abbildungen (25 Farbabbildungen)
40 Tabellen
Handbuch/Nachschlagewerk
Kurzbeschreibung
Current challenges and opportunities in the design and operation of bioreactors for high-value products in the biomedical and chemical industries are discussed in this expert handbook, including soft sensor monitoring, multi-product reactors, and for stem cell production.
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In this expert handbook both the topics and contributors are selected so as to provide an authoritative view of possible applications for this new technology. The result is an up-to-date survey of current challenges and opportunities in the design and operation of bioreactors for high-value products in the biomedical and chemical industries.
Combining theory and practice, the authors explain such leading-edge technologies as single-use bioreactors, bioreactor simulators, and soft sensor monitoring, and discuss novel applications, such as stem cell production, process development, and multi-product reactors, using case studies from academia as well as from industry. A final section addresses the latest trends, including culture media design and systems biotechnology, which are expected to have an increasing impact on bioreactor design.
With its focus on cutting-edge technologies and discussions of future developments, this handbook will remain an invaluable reference for many years to come.
Bioreactors for expansion of induced pluripotent stem cells and their differentiation to cardiac cells
Scale up of stem cell manufacture for cell therapy needs
Culturing entrapped hESC in continuous stirred reactors
Artificial liver bioreactor design
Design of microbioreactor system for process development, Multivariate modeling for bioreactor monitoring and control
Rational integration of bioreactors with primary recovery
Virtual operator training simulators for bioreactors
Soft sensor monitoring and control of bioreactors
Coping with physiological stress in recombinant protein production by bioreactor design
The design bottlenecks with single use bioreactors
The Bioreactor-on a-Chip
Multibioreactors and Design-of-Experiments
Culture media design
Systems biotechnology
