Hydrogel Micro and Nanoparticles

FOREWORD

PREFACE

THERMALLY SENSITIVE MICROGELS: FROM BASIC SCIENCE TO APPLICATIONS
Introduction
Theoretical Background
Basic Physics of Microgels
Applications
Conclusions

THERMOSENSITIVE CORE?SHELL MICROGELS: BASIC CONCEPTS AND APPLICATIONS
Introduction
Volume Transition in Single Particles
Concentrated Suspensions: 3D Crystallization
Particles on Surfaces: 2D Crystallization
Concentrated Suspensions: Rheology
Core - Shell Particles as Carriers for Catalysts
Conclusion

CORE - SHELL PARTICLES WITH A TEMPERATURE-SENSITIVE SHELL
Introduction
Preparation of Core - Shell Particles with a Temperature-Sensitive Shell
Preparation of Hairy Particles with Temperature-Sensitive Hair
Properties, Functions and Applications of Core - Shell Particles with a Temperature-Sensitive Shell
Conclusions

PH-RESPONSIVE NANOGELS: SYNTHESIS AND PHYSICAL PROPERTIES
Introduction
Preparation Techniques for pH-Responsive Nanogels
Structural Properties of pH-Responsive Nanogels
Swelling of pH-Responsive Nanogels
Rheological Behavior of pH-Responsive Nanogels
Approach to Model pH-Responsive Nanogel Properties
Osmotic Compressibility of pH-Responsive Nanogels in Colloidal Suspensions
Conclusions and Future Perspectives

POLY(N-VINYLCAPROLACTAM) NANO- AND MICROGELS
Introduction
Poly(N-Vinylcaprolactam): Synthesis, Structure and Properties in Solution
Thermal Behavior of Poly(N-Vinylcaprolactam) in Water
PVCL Nano- and Microgels
Conclusions

DOUBLY CROSSLINKED MICROGELS
Introduction
Methods of Preparation
Methods of Characterization
Morphology
Properties
Potential Applications
Conclusion

ATRP: A VERSATILE TOOL TOWARD UNIFORMLY CROSSLINKED HYDROGELS WITH CONTROLLED ARCHITECTURE AND MULTIFUNCTIONALITY
Incorporating Crosslinking Reactions into Controlled Radical Polymerization
Effect of Network Homogeneity on Thermoresponsive Hydrogel Performance
Gel Networks Containing Functionalized Nanopores
Toward Micro- and Nano-Sized Hydrogels by ATRP

NANOGEL ENGINEERING BY ASSOCIATING POLYMERS FOR BIOMEDICAL APPLICATIONS
Introduction
Preparation of Associating Polymer-Based Nanogels
Functions of Self-Assembled Nanogels
Application of Polysaccharide Nanogels to DDS
Integration of Nanogels
Conclusion and Perspectives

MICROGELS AND BIOLOGICAL INTERACTIONS
An Introduction to Polymer Biomaterials
Drug Delivery
Biomaterial Films
Conclusion

OSCILLATING MICROGELS DRIVEN BY CHEMICAL REACTIONS
Introduction
Types of Oscillating Microgels
Synthesis and Fabrication of Oscillating Microgels
Control of Oscillatory Behavior
Flocculating/Dispersing Oscillation
Concluding Remarks

SMART MICROGEL/NANOPARTICLE HYBRIDS WITH TUNABLE OPTICAL PROPERTIES
Introduction
Synthesis of Hybrid Gels
Characterization of Hybrid Gels
Hybrid Microgels with Plasmon Properties
Photoluminescent Hybrid Microgels
Summary

MACROSCOPIC MICROGEL NETWORKS
Introduction and Motivation
Preparation of Microgel Networks
Applications of Microgel Networks
Conclusions and Future Outlook

COLOR-TUNABLE POLY (N-ISOPROPYLACRYLAMIDE) MICROGEL-BASED ETALONS: FABRICATION, CHARACTERIZATION, AND APPLICATIONS
Introduction
Microgel-Based Photonic Materials
Conclusions and Future Directions

CRYSTALS OF MICROGEL PARTICLES
Introduction
Theoretical Background and Experimental Methods
Determining and Modeling the Particle Form Factor
Structure Factor of Concentrated Suspensions
Final Remarks and Future Directions

DYNAMICAL ARREST AND CRYSTALLIZATION IN DENSE MICROGEL SUSPENSIONS
Introduction
Methods
Synthesis and Responsive Properties
Structural and Dynamic Properties of Neutral Microgels
Structural and Dynamic Properties of Soft and Weakly Charged Microgels
Conclusions and Outlook: Probing Anisotropic Interactions

L. Andrew Lyon is a Professor in the School of Chemistry and Biochemistry at the Georgia Institute of Technology, Atlanta, USA. After his PhD in Physical Chemistry from Northwestern University he joined Penn State University as a postdoctoral research associate before pursuing
his independent academic career at the Georgia Institute of Technology. Professor Lyon has authored more than 100 articles, contributed to nine books and holds seven patents. His research interests center around the development and implementation of new materials, particularly
hydrogel nanoparticles, for applications in bioanalysis and regenerative medicine.

Michael J. Serpe is Professor in the Department of Chemistry at the University of Alberta, Canada. He completed his PhD in Analytical Chemistry at the Georgia Institute of Technology and then held positions as postdoctoral fellow at the University of Melbourne, Australia, at
World Precision Instruments, Inc., and at Duke University, USA. Professor Serpe has published more than 30 peer-reviewed articles and has delivered numerous invited lectures globally. His group is interested in understanding the fundamental properties of soft, responsive, functional, polymeric materials for a myriad of applications.

L. A. Lyon, Georgia Institute of Technology, Atlanta, USA; M. J. Serpe, University of Alberta, Alberta, Canada