Analysis of Microarray Data
A Network-Based Approach
Quantitative and Network Biology

1. Auflage Februar 2008
XX, 418 Seiten, Hardcover
127 Abbildungen (29 Farbabbildungen)
41 Tabellen
Monographie
Kurzbeschreibung
Overview of cutting-edge approaches to the analysis of microarray data - a technology of major importance throughout the life and medical sciences
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This book is the first to focus on the application of mathematical networks for analyzing microarray data. This method goes well beyond the standard clustering methods traditionally used.
From the contents:
* Understanding and Preprocessing Microarray Data
* Clustering of Microarray Data
* Reconstruction of the Yeast Cell Cycle by Partial Correlations of Higher Order
* Bilayer Verification Algorithm
* Probabilistic Boolean Networks as Models for Gene Regulation
* Estimating Transcriptional Regulatory Networks by a Bayesian Network
* Analysis of Therapeutic Compound Effects
* Statistical Methods for Inference of Genetic Networks and Regulatory Modules
* Identification of Genetic Networks by Structural Equations
* Predicting Functional Modules Using Microarray and Protein Interaction Data
* Integrating Results from Literature Mining and Microarray Experiments to Infer Gene Networks
The book is for both, scientists using the technique as well as those developing new analysis techniques.
Comparative Analysis of Clustering Methods for Microarray Data
Finding Verified Edges in Genetic/Gene Networks: Bilayer Verification for Network Recovery in the Presence
Computational Inference of Biological Causal Networks - Analysis of Therapeutic Compound Effects
Reverse Engineering Gene Regulatory Networks with Various Machine Learning Methods
Statistical Methods for Inference of Genetic Networks and Regulatory Modules
A Model of Genetic Networks with Delayed Stochastic Dynamics
Probabilistic Boolean Networks as Models for Gene Regulation
Structural Equation for Identification of Genetic Networks
Detecting Pathological Pathways of a Complex Disease by a Comparative Analysis of Networks
Predicting Functional Modules Using Microarray and Protein Interaction Data
Computational Reconstruction of Transcriptional Regulatory Modules of the Yeast Cell Cycle
Pathway-Based Methods for Analyzing Microarray Data
The Most Probable Genetic Interaction Networks Inferred from Gene Expression Patterns
Matthias Dehmer studied mathematics at the University of Siegen, Germany, and received his PhD in Computer Science from the Technical University of Darmstadt, Germany. Currently, he holds a research position at Vienna University of Technology, Institute of Discrete Mathematics and Geometry in Vienna, Austria.