John Wiley & Sons Epigenetics and Health Cover "This book successfully conveys that we are in the early stages of understanding epigenetic phenomen.. Product #: 978-1-119-30798-3 Regular price: $87.76 $87.76 Auf Lager

Epigenetics and Health

A Practical Guide

McCulley, Michelle

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1. Auflage Februar 2024
160 Seiten, Softcover
Wiley & Sons Ltd

ISBN: 978-1-119-30798-3
John Wiley & Sons

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"This book successfully conveys that we are in the early stages of understanding epigenetic phenomena, and McCulley admirably explains why this new discipline is important, even if significant hurdles remain before we understand enough about epigenetics to use that information when designing medical or nutritional/lifestyle interventions." -David S. Moore, The Quarterly Review of Biology, March 2025, Volume 100, Number 1 pp. 43 - 44
An incisive and contemporary discussion of epigenetic phenomena applied to human health and disease

Epigenetics and Health: A Practical Guide delivers a thorough and insightful exploration of the basic principles of gene function, gene regulation, and gene expression. The author explains how epigenetic modifications alter gene expression and demonstrate the role played by environmental factors--including nutrition, exercise, toxins, and stress--in gene regulation, as well as their potential health consequences.

The book presents current methods for analyzing epigenetic variation, including NGS applications and bioinformatic analysis.

Readers will be encouraged to question, analyze, and critically appraise the literature on epigenetics to further develop their understanding. They'll also find:

* Explorations of epigenetic mechanisms, homeostasis, and the potential for manipulating the epigenome

* Practical discussions of methods for epigenetic analyses

* How to address cancer epigenetics, mental health epigenetics, and guidance on developing an epigenetics research project

Epigenetics and Health: A Practical Guide will benefit practicing geneticists and medical geneticists seeking insights into epigenetic phenomena applied to human health and disease.

Preface



Chapter 1: How do genes work?



Chapter 2: What is Epigenetics?

Chapter 3: Epigenetic mechanisms, homeostasis and potential for manipulating the epigenome



Chapter 4: Methods for epigenetic analyses

Chapter 5: Aging and epigenetic variation

Chapter 6: Cancer Epigenetics

Chapter 7: Epigenetics and Mental health

Chapter 8: Implications of epigenetic research and Getting Started
Michelle McCulley, PhD, is an Associate Professor in the Department of Pathology and Molecular Medicine at the University of Otago in New Zealand. Her research is focused on the epigenetic regulation of our genes, particularly as it relates to environment, health, and disease.

M. McCulley, University of Otago, New Zealand