Wiley-VCH, Weinheim Polymorphism Cover This handbook emphasizes why solid-state issues are important, what approaches should be taken to av.. Product #: 978-3-527-31146-0 Regular price: $195.33 $195.33 Auf Lager

Polymorphism

in the Pharmaceutical Industry

Hilfiker, Rolf (Herausgeber)

Cover

1. Auflage Februar 2006
XIX, 414 Seiten, Hardcover
156 Abbildungen (8 Farbabbildungen)
19 Tabellen
Handbuch/Nachschlagewerk

ISBN: 978-3-527-31146-0
Wiley-VCH, Weinheim

Wiley Online LibraryProbekapitel

Kurzbeschreibung

This handbook emphasizes why solid-state issues are important, what approaches should be taken to avoid problems and exploits opportunities of solid state properties in the field of pharma-, agro- and fine chemical industry.

Jetzt kaufen

Preis: 209,00 €

Preis inkl. MwSt, zzgl. Versand

Euro-Preise für Wiley-VCH- und Ernst & Sohn-Titel sind nur für Deutschland gültig. In EU-Ländern gilt die lokale Mehrwertsteuer. Portokosten werden berechnet.

- Gedruckte Ausgabe vergriffen -

Weitere Versionen

pdf

Edited by one of the leading experts in the field, this handbook emphasizes why solid-state issues are important, which approaches should be taken to avoid problems and exploit the opportunities offered by solid state properties in the pharmaceutical and agricultural industries.
With its practical approach, this is at once a guideline for development chemists just entering the field as well as a high-quality source of reference material for specialists in the pharmaceutical and chemical industry, structural chemists, physicochemists, crystallographers, inorganic chemists, and patent departments.

Relevance of Solid-state Properties for Pharmaceutical Products
Thermodynamics of Polymorphs
Characterization of Polymorphic Systems using Thermal Analysis
Solid-state NMR Spectroscopy
Vibrational Spectroscopic Methods in Pharmaceutical Solid-state Characterization
Crystallography for Polymorphs
Light Microscopy
The Importance Solvates
Physical Characterization of Hygroscopicity in Pharmaceutical Solids
The Amorphous State
Approaches to Polymorphism Screening
Salt Selection
Processing-induced Phase Transformations and their Implications on Pharmaceutical Product Quality
Polymorphism and Patents from A Chemist's Point of View
Scientific Considerations of Pharmaceutical Solid Polymorphism in Regulatory Applications
"...ist dem Buch ein großer Leserkreis zu wünschen, und vor allem für Studierende wird die Lektüre ein großer Gewinn sein, da in den meisten Grundvorlesungen der Chemie das Thema Polymorphie ausgelassen wird. Darüber hinaus ist es Wissenschaftlern in der pharmazeutischen Industrie und an Hochschulen, die sich für die Charakterisierung organischer Festkörper interessieren, sehr zu empfehlen." Angewandte Chemie
After gaining his PhD in physical chemistry from Basel University, Switzerland, Rolf Hilfiker did his postdoc at Stony Brook, USA. He returned to Basel as a research fellow, initially at the university and then at Ciba-Geigy. In 1997 he became head of Stability & Kinetics group at Novartis, joining Solvias two years later where he is currently head of the department Solid-State Development. Dr. Hilfiker has taught physical chemistry in New York and Basel, and is a recipient of the Jacottet-Küng Award and a Treubel Fellowship.
He is author of more than 50 scientific publications in various areas of physical chemistry.

R. Hilfiker, Solvias AG, Basel, Switzerland