Vaccines and Autoimmunity
1. Auflage Juni 2015
400 Seiten, Hardcover
Wiley & Sons Ltd
In light of the discovery of Autoimmune Syndrome Induced by Adjuvants, or ASIA, Vaccines and Autoimmunity explores the role of adjuvants - specifically aluminum in different vaccines - and how they can induce diverse autoimmune clinical manifestations in genetically prone individuals.
Vaccines and Autoimmunity is divided into three sections; the first contextualizes the role of adjuvants in the framework of autoimmunity, covering the mechanism of action of adjuvants, experimental models of adjuvant induced autoimmune diseases, infections as adjuvants, the Gulf War Syndrome, sick-building syndrome (SBS), safe vaccines, toll-like receptors, TLRS in vaccines, pesticides as adjuvants, oil as adjuvant, mercury, aluminum and autoimmunity. The following section reviews literature on vaccines that have induced autoimmune conditions such as MMR and HBV, among others. The final section covers diseases in which vaccines were known to be the solicitor - for instance, systemic lupus erythematosus - and whether it can be induced by vaccines for MMR, HBV, HCV, and others.
Edited by leaders in the field, Vaccines and Autoimmunity is an invaluable resource for advanced students and researchers working in pathogenic and epidemiological studies.
General Mechanisms:
The mosaic of autoimmunity (Y. Schoenfeld, J.M. Ananya, M. Arango)
Adjuvants and autoimmunity ((E. Israeli, Y. Schoenfeld)
Infections as adjuvants and autoimmunity N. Rose et al)
Experimental models of adjuvants (A. Doria, M. Gatto)
Aluminum as adjuvant and its toxicity (L. Tomljenovic, C. Shaw)
Mercury and autoimmunity (P. Cruz, H. Amital)
Heavy metals and their involvement in autoimmunity (V. Stejskal)
Vaccine and autoimmunity (N. Agmon-Levin, Y. Schoenfeld)
Genetics (J-M, Anaya)
TABLES:
Composition of all vaccines (from N. Agnon-Levin)
Schedule of all vaccines (from L. Tomljenovic)
Section B
Vaccines causing autoimmune diseases
MMR (C. Perricone et al)
Yellow Fever (R. Levy et al)
Tdt (M. Blank, N. Agmon-Levin)
HBV (D. Bogdanos)
HCV (Y. Zafir)
HPV (L. Jara)
Influenza (L. Jara)
Meningococcal vaccine (R. Manna et al)
Pneumococcal vaccine (N. Agmon-Levin et al)
Section C:
Diseases induced by vaccines
SLE (S. Navarra, G. Zandman-Godard)
Vasculitis (S. Kivity)
Rheumatoid arthritis (M. Lidar)
Multiple sclerosis (J. Chapman et al)
MCTD (H. Amital)
Alopcia areata (N. Agmon-Levin)
MMF (R. Gherardi et al)
ITP (C. Perricone, M. Rinaldi)
Type 1 diabetes (L. Cantarini, A. Doria)
Narcolepsy (O. Vaarala)
Celiac Disease (A. Lerner)
Polimyalgia Rheumatica (R. Manna)
APS (P. Tapias Cruz, M. Blank)
GBS (J. Chapman et al)
ADEM (G. Zandman-Goddard)
Fibromyalgia (D. Buskila)
Chronic fatigue syndrome (H. Amital)
Systemic sclerosis (A. Balbir)
Nancy Agmon-Levin is a specialist in Clinical Immunology and Allergology, and serves as Deputy Head of the Zabludowicz Center for Autoimmune Diseases, Sheba Medical Center in Tel Hashomer, Israel. She is also President of the Israel Association for Allergy and Clinical Immunology (IAACI).
Lucija Tomljenovic is a Senior Postdoctoral Fellow in the Neural Dynamics Research Group at the University of British Columbia in Vancouver, BC, Canada.
