Abdominal Aortic Aneurysm

An increase in incidence of abdominal aortic aneurysm is predicted
as an extension of the advancing age of our population. Novel
strategies for treatment and prevention need to be considered.
Interdisciplinary approaches to this disease will aid in prevention
and treatment. This volume will integrate new insights into the
etiology and pathology of aneurismal disease, including physiologic
and genetic causes.



Several educational objectives have been met in this volume. The
contributors assess the benefits of risk of rupture assessment at
different ages and thresholds of abdominal aortic aneurysm in the
context of epidemiologic studies, examine the use of animal models
in the study of abdominal aortic aneurysm and its underlying
pathobiology, and integrate data on susceptibility and genetic
causes of abdominal aortic aneurysms.

The increase in abdominal aortic aneurysms (AAA) is viewed from
the perspective of epidemiology, and initiatives to prevent death
from rupture are discussed. Animal models and their relevance to
pathophysiology and prevention are also presented, and the
interventional pharmacology is also considered from the perspective
of enzymology.

In addition, chapters covering the biological aspects of the
endovascular devices used to repair abdominal aortic aneurysm and
the molecular biology and immunology in abdominal aortic aneurysm
are included.

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