A Statistical Approach to Genetic Epidemiology
Concepts and Applications, with an e-learning platform
2. Edition March 2010
XXIV, 498 Pages, Softcover
250 Pictures (50 Colored Figures)
Textbook
Short Description
The second edition of this very successful advanced textbook is thoroughly updated and significantly expanded. The title has again many problems and solutions and it comes now colour figures and optionally with a custom-developed e-learning course.
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Further versions
This is the second edition of the successful textbook written by the prize-winning scientist Andreas Ziegler, former President of the German Chapter of the International Biometric Society, and Inke König, who has been teaching the subject over many years.
The book gives a comprehensive introduction into the relevant statistical methods in genetic epidemiology. The second edition is thoroughly revised, partly rewritten and includes now chapters on segregation analysis, twin studies and estimation of heritability. The book is ideally suited for advanced students in epidemiology, genetics, statistics, bioinformatics and biomathematics.
Like in the first edition the book contains many problems and solutions and it comes now optionally with an e-learning course created by Friedrich Pahlke. This e-learning course has been developed to complement the book. Both provide a unique support tool for teaching the subject.
Molecular Genetics
Formal Genetics
Genetic Markers
Data Quality
LINKAGE ANALYSIS AND FAMILY STUDIES
Genetic Map Distances
Model Based Linkage Analysis
Model Free Linkage Analysis for Binary Traits
Model Free Linkage Analysis for Quantitative Traits
Family Studies not Involving Genetic Markers
ASSOCIATION ANALYSIS
Fundamental Concepts of Association Analyses
Association Analysis with Unrelated Individuals
Family Based Association Analysis
Haplotypes
GWAs
Appendix
Solutions
References
Inke R. König studied psychology at the universities of Marburg (Germany) as a scholar of the German National Academic Foundation and Dundee (Scotland) with a grant from the German Academic Exchange Service (DAAD). She has done research work at the Institute of Medical Biometry and Epidemiology in Marburg and since 2001 at the Institute of Medical Biometry and Statistics in Lübeck. In 2004, she became vice director of the latter and also received the Fritz-Linder-Forum-Award from the German Association for Surgery. Besides holding the certificate "Biometrics in Medicine", she has collected teaching experience since 1998 as a lecturer for biomathematics, behavioural genetics, clinical epidemiology, genetic epidemiology, and evidence-based medicine.
Friedrich Pahlke is Dipl. Inf. at the Institute for Medical Biometry and Statistics at the University Clinic Schleswig-Holstein in Lübeck. He has created the e-learning course which is optionally available with the book.
