Freeze-Drying
3. Edition February 2018
440 Pages, Hardcover
76 Pictures
Practical Approach Book
Short Description
In this completely revised and updated edition, application aspects and supplying criteria for the selection of laboratory or industrial processes are the focus of the book. The reader is getting information about plant and process automation, troubleshooting and upscaling, too.
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Further versions
This completely updated and enlarged third edition of the classic text adopts a practical approach to describe the fundamentals of freeze-drying, backed by many explanatory examples.
Following an introduction to the fundamentals, the book goes on to discuss process and plant automation as well as methods to transfer pilot plant qualifications and process data to production. An entire section is devoted to a large range of different pharmaceutical, biological, and medical products. New to this edition are chapters on antibodies, freeze-dry microscopy, TEMPRIS, microwave freeze-drying, spray freeze-drying, and PAT.
Their many years of experience in freeze-drying enable the authors to supply valuable criteria for the selection of laboratory, pilot and production plants, discussing the advantages, drawbacks and limitations of different plant designs. Alongside guidelines for the evaluation and qualification of plants and processes, the author also includes a troubleshooting section.
Freezing
Drying
Storing
PLANT TECHNOLOGY
Plants for freezing
Components of a freeze-drying plant
Plants for batches up to 10 kg
Large scale plant
Food production plant
PHARMACEUTICAL, BIOLOGICAL, AND MEDICAL PRODUCTS
Proteins and hormones
Viruses; serums, bacteria, yeasts
Antibiotics
Liposomes and nanoparticles
Transplants
Antibodies
POINTS OF GENERAL INTEREST
Norms and abbreviations
Validation of processes and plant
He worked already together with Dr. Georg-Wilhelm Oetjen (who passed away 2015) on the second edition of ?Freeze-Drying? and has now taken over the authorship for the third edition.
